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Bell, Graeme
One or more keywords matched the following items that are connected to Bell, Graeme
Item TypeName
Concept Bacterial Outer Membrane Proteins
Concept DNA-Binding Proteins
Concept Membrane Proteins
Concept Nerve Tissue Proteins
Concept Monosaccharide Transport Proteins
Concept Heat-Shock Proteins
Concept Muscle Proteins
Concept Protein Precursors
Concept Protein Binding
Concept Protein Conformation
Concept Proto-Oncogene Proteins
Concept Proteins
Concept Thyroxine-Binding Proteins
Concept Protein Biosynthesis
Concept Protein Subunits
Concept Cysteine Proteinase Inhibitors
Concept Protein Structure, Tertiary
Concept RNA-Binding Proteins
Concept MyoD Protein
Concept HSP70 Heat-Shock Proteins
Concept ras Proteins
Concept Apoptosis Regulatory Proteins
Concept Multidrug Resistance-Associated Proteins
Concept Drosophila Proteins
Concept Protein Tyrosine Phosphatases
Concept Protein Structure, Secondary
Concept Protein Folding
Concept Intercellular Signaling Peptides and Proteins
Concept Green Fluorescent Proteins
Concept HSC70 Heat-Shock Proteins
Concept Proto-Oncogene Proteins c-raf
Concept WT1 Proteins
Concept Recombinant Proteins
Concept Protein Phosphatase 1
Concept Sterol Regulatory Element Binding Protein 1
Concept Adaptor Proteins, Signal Transducing
Concept Sex-Determining Region Y Protein
Concept GTP-Binding Proteins
Concept Homeodomain Proteins
Concept HSP90 Heat-Shock Proteins
Concept Macrophage Inflammatory Proteins
Concept Tumor Suppressor Proteins
Concept Glycine Plasma Membrane Transport Proteins
Concept Mutant Proteins
Concept Transcription Factor 7-Like 2 Protein
Concept Agouti Signaling Protein
Concept AMP-Activated Protein Kinases
Concept Insulin Receptor Substrate Proteins
Concept LIM-Homeodomain Proteins
Concept Intracellular Signaling Peptides and Proteins
Concept Calcium-Binding Proteins
Concept Carrier Proteins
Concept Luminescent Proteins
Concept Neoplasm Proteins
Concept Nuclear Proteins
Concept Recombinant Fusion Proteins
Concept Cyclic AMP-Dependent Protein Kinases
Concept Protein Isoforms
Concept Protein Array Analysis
Concept Proto-Oncogene Proteins c-akt
Academic Article Pharmacological properties of two cloned somatostatin receptors.
Academic Article Hormonal/metabolic regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
Academic Article Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism.
Academic Article Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation.
Academic Article Leptin, the obese gene product, rapidly modulates synaptic transmission in the hypothalamus.
Academic Article Novel MODY3 mutations in the hepatocyte nuclear factor-1alpha gene: evidence for a hyperexcitability of pancreatic beta-cells to intravenous secretagogues in a glucose-tolerant carrier of a P447L mutation.
Academic Article Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
Academic Article JAK/STAT eats the fat.
Academic Article Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins.
Academic Article Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
Academic Article Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)
Academic Article Mutations in the hepatocyte nuclear factor-1alpha gene in MODY and early-onset NIDDM: evidence for a mutational hotspot in exon 4.
Academic Article Searching for NIDDM susceptibility genes: studies of genes with triplet repeats expressed in skeletal muscle.
Academic Article Cloning and characterization of exodus, a novel beta-chemokine.
Academic Article Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene.
Academic Article Molecular analysis of the fructose transporter gene (GLUT5) in isolated fructose malabsorption.
Academic Article Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues.
Academic Article Increase in serum leptin and uterine leptin receptor messenger RNA levels during pregnancy in rats.
Academic Article Mutations in the hepatocyte nuclear factor-1alpha/MODY3 gene in Japanese subjects with early- and late-onset NIDDM.
Academic Article Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3).
Academic Article Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM.
Academic Article Activation of a protein tyrosine phosphatase and inactivation of Raf-1 by somatostatin.
Academic Article Nature or nurture: an insightful illustration from a Chinese family with hepatocyte nuclear factor-1 alpha diabetes (MODY3)
Academic Article Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects.
Academic Article Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1 beta.
Academic Article Linkage analysis of maturity-onset diabetes of the young with microsatellite polymorphisms. No linkage to ADA or GLUT2 genes in two families.
Academic Article beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic differentiation 4 (NEUROD4) in Japanese patients with MODY.
Academic Article Expression and regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
Academic Article A simple test for the high-frequency P291fsinsC mutation in the HNF1 alpha/MODY3 gene.
Academic Article A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance.
Academic Article Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.
Academic Article Reduced pancreatic polypeptide response to hypoglycemia and amylin response to arginine in subjects with a mutation in the HNF-4alpha/MODY1 gene.
Academic Article Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1.
Academic Article Beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the hepatocyte nuclear factor-3beta gene (HNF3B) in Japanese patients with maturity-onset diabetes of the young.
Academic Article Fructose transporter in human spermatozoa and small intestine is GLUT5.
Academic Article Calpains play a role in insulin secretion and action.
Academic Article No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY.
Academic Article Nuclear translocation of SHP and visualization of interaction with HNF-4alpha in living cells.
Academic Article A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.
Academic Article Genetic variants of hepatocyte nuclear factor-1beta in Chinese young-onset diabetic patients with nephropathy.
Academic Article Control of pancreas and liver gene expression by HNF transcription factors.
Academic Article Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells.
Academic Article RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets.
Academic Article Dual promoter structure of ZFP106: regulation by myogenin and nuclear respiratory factor-1.
Academic Article Imaging Beta cell development in real-time using pancreatic explants from mice with green fluorescent protein-labeled pancreatic Beta cells.
Academic Article Gene symbol: IPF1. Disease: MODY 4.
Academic Article Calpain system regulates muscle mass and glucose transporter GLUT4 turnover.
Academic Article Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy.
Academic Article Insulin gene mutations as a cause of permanent neonatal diabetes.
Academic Article Subcellular recruitment by TSG118 and TSPYL implicates a role for zinc finger protein 106 in a novel developmental pathway.
Academic Article Association of the (AU)AT-rich element polymorphism in PPP1R3 with hormonal and metabolic features of polycystic ovary syndrome.
Academic Article From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation.
Academic Article Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome.
Academic Article Obesity and hyperinsulinemia in a family with pancreatic agenesis and MODY caused by the IPF1 mutation Pro63fsX60.
Academic Article Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted.
Academic Article Calpain-10 gene and protein expression in human skeletal muscle: effect of acute lipid-induced insulin resistance and type 2 diabetes.
Academic Article TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.
Academic Article Identification of two novel amino acid polymorphisms in beta-cell/liver (GLUT2) glucose transporter in Japanese subjects.
Academic Article Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism.
Academic Article Human thyroxine-binding globulin gene: complete sequence and transcriptional regulation.
Academic Article Core transcriptional regulatory circuitry in human hepatocytes.
Academic Article Gi alpha 3 and G(o) alpha selectively associate with the cloned somatostatin receptor subtype SSTR2.
Academic Article Mutation of an aspartate at residue 89 in somatostatin receptor subtype 2 prevents Na+ regulation of agonist binding but does not alter receptor-G protein association.
Academic Article A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones.
Academic Article Localization of the gene encoding a neutral amino acid transporter-like protein to human chromosome band 19q13.3 and characterization of a simple sequence repeat DNA polymorphism.
Academic Article Localization of the genes encoding two transcription factors, LMX1 and CDX3, regulating insulin gene expression to human chromosomes 1 and 13.
Academic Article G protein-activated inwardly rectifying potassium channel (GIRK1/KGA) mRNA in adult rat heart and brain by in situ hybridization histochemistry.
Academic Article Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2.
Academic Article Agonists and antagonists bind to different domains of the cloned kappa opioid receptor.
Academic Article Glucokinase: structural analysis of a protein involved in susceptibility to diabetes.
Academic Article Immunological detection of isoforms of the somatostatin receptor subtype, SSTR2.
Academic Article Structure and function of ASP, the human homolog of the mouse agouti gene.
Academic Article Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase.
Academic Article Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1.
Academic Article A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding.
Academic Article In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes.
Academic Article Organization of the human GLUT2 (pancreatic beta-cell and hepatocyte) glucose transporter gene.
Academic Article Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism.
Academic Article Genetic contribution of polymorphism of the GLUT1 and GLUT4 genes to the susceptibility to type 2 (non-insulin-dependent) diabetes mellitus in different populations.
Academic Article Mutations in the hepatocyte nuclear factor-1alpha gene are a common cause of maturity-onset diabetes of the young in the U.K.
Academic Article Localization of human homeodomain transcription factor insulin promoter factor 1 (IPF1) to chromosome band 13q12.1.
Academic Article Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators.
Academic Article Organ alchemy: producing insulin in the liver.
Academic Article Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family.
Academic Article 5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways.
Academic Article Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic ß-cells.
Academic Article Cloning of rat and mouse P2Y purinoceptors.
Academic Article Regulation of expression of the human fructose transporter (GLUT5) by cyclic AMP.
Academic Article Molecular model of human beta-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B.
Academic Article Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylylcyclase.
Academic Article Dinucleotide repeat polymorphism at the human ribophorin II locus (RPN2) on chromosome 20q.
Academic Article Classification and nomenclature of somatostatin receptors.
Academic Article Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor.
Academic Article A tyrosine phosphatase is associated with the somatostatin receptor.
Academic Article Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms.
Academic Article Assignment of SLC6A9 to human chromosome band 1p33 by in situ hybridization.
Academic Article Structure and function of mammalian facilitative sugar transporters.
Academic Article Activation of human somatostatin receptor type 2 causes inhibition of cell growth in transfected HEK293 but not in transfected CHO cells.
Academic Article Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.
Academic Article Persistence of two genotypes of Neisseria gonorrhoeae during transmission.
Academic Article In vitro scan for enhancers at the TCF7L2 locus.
Academic Article Purification of multiple heat shock proteins from a single tumor sample.
Academic Article Role of BH3-only molecules Bim and Puma in ß-cell death in Pdx1 deficiency.
Academic Article Cost-effectiveness of MODY genetic testing: translating genomic advances into practical health applications.
Academic Article Microcephaly, epilepsy, and neonatal diabetes due to compound heterozygous mutations in IER3IP1: insights into the natural history of a rare disorder.
Academic Article Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice.
Academic Article Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin.
Academic Article Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin.
Academic Article Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.
Academic Article A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
Academic Article A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.
Academic Article Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men.
Concept Bcl-2-Like Protein 11
Grant MOLECULAR MECHANISMS/BETA CELL DYSFUNCTION IN DIABETES
Grant A Fly Model of Complex Protein Misfolding Disease
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  • Misfolding